Bone Abstracts

Objectives: The linear growth of child is characterized by the presence of phases of growth spurt which allowed to rich the peak growth to the end of puberty. Acceleration of velocity of linear growth required the adequate calcium and vitamin D supplementation necessary for mineralization of bone matrix and osteoblast proliferation.The aim of our study was to evaluate changes of serum concentrations of vitamin D during the growth phases.<p class="abs...

Children with chronic gastroduodenitis (CGD) have decreased absorption of nutrients, minerals particularly, which can influence on bone strength and linear growth.Objectives: We evaluated bone mineral density (BMD) in children with CGD and compared with healthy individuals.Methods: BMD was measured in 97 children aged 5–13 years by lumbar spine DXA (DPX MD+, Lunar) with pediatric reference database. BMD was evaluated according...

Objectives: Juvenile idiopathic arthritis (JIA) – is a chronic inflammatory disease of joints which can affect optimal linear growth, risk of fractures and bone quality during the childhood and adult life. The aim of our study was to detect the simple clinical and laboratorial markers which can predict the realization of low bone mineral density (LBMD <−2 S.D.) in children with JIA.Methods: 198 children (82 boys and 116 girl...

Objectives: We evaluated role of disease activity and genetic factors in fractures predisposing among juvenile idiopathic arthritis (JIA) children.Methods: Bone mineralization parameters were detected by dual-energy X-ray absorptiometry of lumbar spine L1–L4 in 197 (81 boys and 116 girls) JIA children. Bone biochemical markers included osteocalcin, C-terminal telopeptides, parathyroid hormone (PTH), Ca, Ca++, P, tota...